HORDB

ID: hor001591
Uniprot ID: Q07981
Protein name: NDPFLRFGKKSDPFLRF-amide
Gene name: NA
Organism: Cornu aspersum (Brown garden snail) (Helix aspersa)
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: Central nervous system.
Disease: NA
Comments: NA
Taxonomy: Cornu (subgenus), Cornu (genus), Helicidae (family), Helicoidea (superfamily), Helicina, Stylommatophora (order), Eupulmonata (superorder), Panpulmonata, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: NDPFLRFGKKSDPFLRF
Length: 17(50-66)
Propeptide: MTSLCLTIAPAVLSLICLSSYGWAEGDTTDNEYLRFGRENNNGYIRFGRNDPFLRFGKKSDPFLRFGKQDPFLRIGRQDPFLRFGKQDPFLRFGKQDPFLRIGKQDPFLRFGRSEPYLRFGRNDPYLRFGRNDPYLRFGRNDPYLRFGRNDPYLRFGKNDPFLRFGKSVDGEIEAGVDAVTLSREHEFAHENAASDRQKRSAYTDAIDKDNSLTSLVREAREASDSNGQINDGKVVEVPVFRDTRNGHYMRFGKK
Signal peptide: MTSLCLTIAPAVLSLICLS
Modification: T17 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Function: Can function as both cardioregulatory hormones and transmitters and may regulate cardiovascular function.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001591_AF2.pdb

hor001591_ESM.pdb

Mass:	236996	Formula:	C99H146N26O24
Absent amino acids:	ACEHIMQTVWY	Common amino acids:	F
pI:	10.77	Basic residues:	4
Polar residues:	3	Hydrophobic residues:	6
Hydrophobicity:	-75.88	Boman Index:	-4572
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	45.88
Instability Index:	4973.53	Extinction Coefficient cystines:	0
Absorbance 280nm:	0